there is common little widdle used in alot of lead breaks, in E for example you would play 12h15p12 on the Bstring then play 14 on the Gstring and repeat.
when i play it, the cleanest picking pattern ive found(playing fast) is to only pick the first note, the 12, and just hammer on when i get to the 14. i find that as i pick the 12 my thumb damps the unwanted open G as you lift off the 14. (i hope that makes sense, but i think most people know the lick i mean)
i just wondered how anyone else does it and if you pick the 14 how you damp the note when you lift off?
a simple one i know :)