Something to keep in mind with PRS is some of their models (e.g. Custom 24) have 24 frets rather than the traditional 22. It felt weird to me. As Jeff pointed out, there are neck options too on LPs...50's style (also called "baseball bat") chunky necks or the 60's slim taper neck.

You have to try them out and see what you think. Personally, I like the variety. I have a strat which has a slim neck, an lp with a 60's slim taper neck, and an lp with a 50's style neck. Sometimes I perfer the feel of one over the other. Some songs I can play better on a thick neck than a thin neck.

With the way prices are rising, I would serisouly consider used...you'll get much more bang for your buck. As long as the guitar wasn't abused, it should be fine. If I ever look to buy a new guitar, I will scour the used market. I've learned the hard way that buying new doesn't always equate to "problem free".