I think LaGrange by ZZT. Just try to find somebody who does recognize that riff. Maybe they can't name the song but they know the riff!

Or if I change my criteria a little then I will say Welcome to the Jungle, GnR. It was just what mainstream rock needed at the time.

the computer in my head (which is as powerful as one from the early 80s, at best) says, "too many variables,, can not compute"