Electric Guitars are the inspiration for cries of "Turn that damn thing down"-Gibson website
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I run guitar-wah-comp-comp-od-chorus-eq-deay-tuner all in a row and I have no sound quality issues. The setup is easy when transporting and does not require any additional channel switchers (i have a channel switch for my amp). By all means try your way, but try in a row as well, because you never know.. You may find something in between.