Though I don't know what type/shape room you are dealing with for sound, nor the number of pieces you are working with I can only recommend trying what I've seen from various performances and their setups. The Wall setup seems to be common, with the drummer being the center of the wall and the bass/rhythm on the wings (sometimes they angle their amps towards the center slightly while standing in front of their own equipment) and the lead guitarist opposite side of the rhythm guitarist (also in front of his angled equipment) and lead singer (if not playing an instrument) as frontman. Of course the amount of "angling in to center" will depend on the size of the room as will the volume of each piece. I've also seen variations, like Joe Bonamassa who uses a similar angled wall setup, but he also screens off his amps while using an additional PA system and soundman to regulate the sound. But that setup seems to be more for a performance than "jamming". Of course I'm no expert, but just wanted to offer some ideas from my observations.
Brian
