the late tommy TEDESCO, (most recorded guitarist ever, top session player in hollywood, founder of MIT)used to say that you should connect chords either by the top or the bottom... he meant by bass movement or by the highest note.. In his video "make a living playing the guitar" he shows several chord progression where he plays random voicings, but with the bass playing the changes... So, in harmonizing your melody, try and choose between all the voicings you know that include the note of your melody, making the note the highest one of your voicing... Then, try connecting the chords by bass movement... Might sound confusing, but it works for me.