Not that easy to explain, as it depends on the amp that you are using.

I use a Fender ROC PRO 7oo.

settindgs as follows:-

SPOTLESS = trb=3 mid=5 bass=5 (normal )

SHATTERED GLASS = gain=3 treb=7 mid=9 bass=5

THICK N CREAMY = gain=7 treb=6 mid=10 bass=2-3

CHUNKY= gain=7 treb=6 mid=8 bass=2-3

AUSTIN BLUES = gain=4 treb=6 mid=8 bass=3

HOT ROD = gain=10 treb=4 mid=3 bass=3

reverb as you like really.

If you go the web site of the maufacturer of your amp they will probably send you details about settings etc.

hope this is of help.